PBSerum

Hyaluronidase is an enzyme that breaks down proteoglycans and hyaluronic acid into low-molecular-weight fragments. Recombinant Hyaluronidase PB3000, with an activity of 1500 IU, is of microbiological origin and is produced using biotechnological methods.

Hyaluronidase PB3000 helps reduce excess polysaccharides responsible for fluid retention in tissues, providing a pronounced draining effect. It reduces osmotic pressure and tissue swelling, decreases the viscosity of hyaluronic acid, and facilitates fluid diffusion within the interstitial space. The enzyme also enhances tissue permeability, improves microcirculation, supports hematoma resorption, and increases the elasticity of scar-altered tissue.

Lipase is a collective term for enzymes capable of breaking down fats and fat-like substances. Lipases are widely found in nature and may be derived from plant, animal, or microbiological sources. They differ significantly in their specificity of action, solubility, optimal pH, and other biochemical properties.

The key advantage of Lipase PB500 is its lack of hormone sensitivity, which explains both its strong lipolytic activity and its favorable tolerability profile. Lipase PB500 reduces adipocyte volume by breaking down triglycerides into glycerol and free fatty acids, helping mobilize localized fat deposits without destroying the adipocyte itself. As a result, its action is highly physiological, gentle, and at the same time effective.

Keratinase PB333 is an enzyme biotechnologically derived from Bacillus licheniformis and produced using an E. coli system. Owing to its specific keratolytic activity, keratinase gently exfoliates keratinized skin cells without causing trauma to the tissue.

It serves as a natural alternative to AHA peels, delivering comparable benefits without irritation, pH disruption, or impairment of the skin barrier. Keratinase PB333 is one of the key components in PBSerum facial enzyme formulations intended for superficial use, including intended for superficial use, including device-assisted procedures, dermapen-assisted applications, and localized topical use.

Collagenase is one of the most powerful proteolytic enzymes, with a specific action on collagen fibers, the primary structural element of connective tissue. Collagenases are the only enzymes capable of specifically recognizing and hydrolyzing native collagen.

The main advantage of Collagenase G/H PB220 lies in the combined use of two collagenase types – G and H – in a precisely balanced ratio, resulting in a pronounced synergistic effect.

Main effects of Collagenase G/H PB220: